Monitoring of nanoparticle reactivity in solution: interaction of l -lysine and Ru nanoparticles probed by chemical shift perturbation parallels regioselective H/D exchange - INSA Toulouse - Institut National des Sciences Appliquées de Toulouse Access content directly
Journal Articles Chemical Communications Year : 2017

Monitoring of nanoparticle reactivity in solution: interaction of l -lysine and Ru nanoparticles probed by chemical shift perturbation parallels regioselective H/D exchange

Abstract

Thanks to new water-soluble Ru nanoparticles (NPs) stabilized by sulfonated NHC ligands, we demonstrate that it is possible to monitor the catalyst/substrate interaction using NMR chemical shift perturbations (CSPs), under conditions that closely resemble those applied during the enantiospecific C–H deuteration of L-lysine. Correlating the pH dependence of the interaction of L-lysine with the surface of the RuNPs and its subsequent deuteration, our study underscores the importance of oriented binding to the surface as a critical factor for H/D exchange.
No file

Dates and versions

hal-02004103 , version 1 (01-02-2019)

Identifiers

Cite

Luis Miguel Martinez-Pietro, Edwin A Baquero, Grégory Pieters, Juan Flores, Ernesto de Jesus, et al.. Monitoring of nanoparticle reactivity in solution: interaction of l -lysine and Ru nanoparticles probed by chemical shift perturbation parallels regioselective H/D exchange. Chemical Communications, 2017, 53 (43), pp.5850-5853. ⟨10.1039/c7cc02445b⟩. ⟨hal-02004103⟩
207 View
0 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More